Former Lab Members

Francisco Bastos de Oliveira
Francisco-2013-small-optmzState University of Rio de Janeiro (UFRJ)

Patrice Ohouo
Postdoctoral Research Fellow, Foley Lab
Sloan-Kettering Institute
New York, NY 

 Patrice Ohouo crop

Laura Jaramillo
Stay-at-Home Mom
Rochester, NY

 Laura-Jaramillo-small-optmz copy

Jacky Munoz
Medical Student
Baylor College of Medicine
Houston, TX

 Jacky-Munoz-small-optmz copy

Odis Ponce
Lab Manager, Phillips Lab
Cancer Institute/NYU Medical Center
New York, NY 


Chu Jian “Frank” Ma
MD/PhD Program
Columbia University

New York, NY

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Jose Renato
University of San Paolo


Arina Perez
State University of Campinas


Arina Perez

Jacob Weiser
Cornell University


Jessica Mendes

Jessica Mendes


Marcus Smolka, PhD

Marcus Smolka is an Associate Professor in the Department of Molecular Biology and Genetics, and a member of the Weill Institute for Cell and Molecular Biology. He received a Ph. D. in Brazil, at the State University of Campinas and worked as a visiting fellow with Dr. Ruedi Aebersold, at the Institute for Systems Biology (Seattle, WA). In 2003, Dr. Smolka moved to San Diego, CA for a post-doctorate at the Ludwig Institute for Cancer Research, working with DNA damage checkpoint kinases and phosphoproteomics in the laboratory of Dr. Huilin Zhou. He joined Cornell in 2008.

Marcus B. Smolka, Ph.D
Weill Institute for Cell and Molecular Biology
Department of Molecular Biology and Genetics
Cornell University
339 Weill Hall
Ithaca, NY 14853-7202

(607)255-0274 (Office)
(607)255-0174 (Lab)

Selected Publications

J Cell Bio (2017) - TOPBP1/Dpb11 plays a conserved role in homologous recombination DNA repair through the coordinated recruitment of 53BP1/Rad9.. Yi Liu, José Renato Cussiol, Jennie Rae Sims, …, Marcus Bustamante Smolka.
Commentary by the Gasser Lab: A game of musical chairs: Pro- and anti-resection factors compete for TOPBP1 binding after DNA damage.

Chromosoma (2016) - Slx4 scaffolding in homologous recombination and checkpoint control: lessons from yeast. Jose Cussiol, Diego Dibitetto, Achille Pellicioli, and Marcus Smolka. [Epub ahead of print] Review.

J Cell Biol (2016) - TOPBP1 takes RADical command in recombinational DNA repair. Yi Liu and Marcus Smolka.

Mol Cell (2015) - Phosphoproteomics Reveals Distinct Modes of Mec1/ATR Signaling during DNA Replication. Francisco Bastos de Oliveira, Dongsung Kim, José Renato Cussiol, Jishnu Das, Min Cheol Jeong, Lillian Doerfler, Kristina Hildegard Schmidt, Haiyuan Yu, Marcus Smolka.

EMBO Journal (2015) - Dampening DNA damage checkpoint signalling via coordinated BRCT domain interactions. José R Cussiol, Carolyn M Jablonowski, Askar Yimit, Grant W Brown, Marcus B Smolka

EMBO Journal (2015) - Assembly of Slx4 signaling complexes behind DNA replication forks. Attila Balint, TaeHyung Kim, David Gallo, Jose Renato Cussiol, Francisco Bastos de Oliveira, Askar Yimit, Jiongwen Ou, Ryuichiro Nakato, Alexey Gurevich, Katsuhiko Shirahige, Marcus Smolka, Zhaolei Zhang, Grant Brown

Nature (2013) - DNA Repair Scaffolds Dampen Checkpoint Signaling by Counteracting the Rad9 Adaptor. Patrice Ohouo, Yi Liu, Francisco M Bastos de Oliveira and Chu Jian "Frank" Ma and Marcus Smolka.

J Biol Chem.(2013) - Interactome analysis reveals ezrin can adopt multiple conformational states. Raghuvir Viswanatha, Jessica Wayt, Patrice Ohouo, Marcus Smolka, Anthony Bretscher.

Cell Cycle (2012) - The many roads to checkpoint activation. Patrice Ohouo and Marcus Smolka.

J Cell Biol (2012) - Local phosphocycling mediated by LOK/SLK restricts ezrin function to the apical aspect of epithelial cells. Raghuvir Viswanatha, Patrice Ohouo, Marcus Smolka, and Anthony Bretscher.

Cell Cycle (2012) - The checkpoint transcriptional response: Make sure to turn it off once you are satisfied. Marcus Smolka, Francisco Bastos de Oliveira, Michael Harris, and Robertus A M de Bruin.

EMBO Journal (2012) - Linking DNA replication checkpoint to MBF cell-cycle transcription reveals a distinct class of G1/S genes. Francisco Bastos de Oliveira, Michael Harris, Pijus Brazauskas, Robertus A M de Bruin and Marcus Smolka.

EMBO Journal (2012) - DNA replication stress differentially regulates G1/S genes via Rad53-dependent inactivation of Nrm1. Anna Travesa, Dwight Kuo, Robertus AM de Bruin, Tatyana I Kalashnikova, Marisela Guaderrama, Kevin Thai, Aaron Aslanian, Marcus Smolka, John R Yates III, Trey Ideker and Curt Wittenberg.

Cell (2011) - TORC1 regulates endocytosis via Npr1-mediated phosphoinhibition of a ubiquitin ligase adaptor. JA MacGurn, PC Hsu, Marcus Smolka and Scott Emr. 147(5):1104-17.

Cell Cycle (2011) - A touching moment for Smc5/6: from ssDNA binding to repair. Patrice Ohouo, Marcus Smolka, (April 2011) (comment on Roy MA, et al. Cell Cycle).

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